1 Foundation domain

Energy & Metabolic Resilience

Your skin's ability to power its own repair. When cellular energy declines, every other repair process slows with it.

You might recognise this as

Skin that looks flat or dull even when you're not tired. Slower recovery after cleansing or environmental stress.

Energy & Metabolic Resilience

The biology

Why energy is the foundation of everything

Barrier recovery, collagen synthesis, DNA repair — all of these require ATP generated by mitochondria. As mitochondrial efficiency and NAD+ availability decline with age, repair slows across every domain.

In younger skin

In younger skin

Fast, efficient repair

Mitochondria run at high capacity. NAD+ is abundant. Skin recovers quickly after daily stress.

With age and stress

With age & stress

Slower, less complete recovery

Mitochondrial efficiency declines. NAD+ falls. Repair becomes slower — damage accumulates faster than it can be corrected.

Key actives

How Evolve supports this domain

These ingredients work together to support mitochondrial efficiency, reduce oxidative burden, and maintain cellular recycling pathways.

NAD+ precursor · energy metabolism

Niacinamide

A precursor of NAD+, niacinamide supports cellular energy metabolism and DNA repair. It works upstream — helping maintain the energy currency all repair processes depend on.

In brief

NAD+ is essential for mitochondrial energy production and DNA repair. Studies show niacinamide can restore NAD+ levels in ageing cells and support collagen synthesis in older fibroblasts.

Niacinamide

Antioxidant · collagen support

Vitamin C

A precursor of NAD+, niacinamide supports cellular energy metabolism and DNA repair. It works upstream — helping maintain the energy currency all repair processes depend on.

In brief

NAD+ is essential for mitochondrial energy production and DNA repair. Studies show niacinamide can restore NAD+ levels in ageing cells and support collagen synthesis in older fibroblasts.

Vitamin C

Stress protection · cellular stability

Extremolytes

A precursor of NAD+, niacinamide supports cellular energy metabolism and DNA repair. It works upstream — helping maintain the energy currency all repair processes depend on.

In brief

NAD+ is essential for mitochondrial energy production and DNA repair. Studies show niacinamide can restore NAD+ levels in ageing cells and support collagen synthesis in older fibroblasts.

Questions

Frequently asked

Topical formulations can't alter systemic energy metabolism, but they can support the local biological environment of the skin — reducing oxidative burden, supporting NAD+ precursor availability, and maintaining the conditions repair processes need to function well.
Topical formulations can't alter systemic energy metabolism, but they can support the local biological environment of the skin — reducing oxidative burden, supporting NAD+ precursor availability, and maintaining the conditions repair processes need to function well.
Topical formulations can't alter systemic energy metabolism, but they can support the local biological environment of the skin — reducing oxidative burden, supporting NAD+ precursor availability, and maintaining the conditions repair processes need to function well.

Find your routine

Not sure which products are most relevant to your skin? Take the quiz and we'll connect your concerns to the biological systems at work.

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